Stronger statin drugs linked to high rates of muscle injuries


Stronger statin drugs linked to high rates of muscle injuriesA new study has identified the cholesterol statin drug Crestor (rosuvastatin) as the one in the class most associated with reports of severe muscle injury.  It, along with other popular statin drugs, are more likely to cause muscle injury when taken at the highest doses.

According to a report this week, researchers at University of California-San Diego School of Medicine have identified rosuvastatin, atorvastatin, simvastatin, pravastatin, and lovastatin as those statin drugs most likely to cause muscle injuries, like pain and weakness.

The study found that the strength and potency of the statin drug taken is a key factor in determining a person’s risk of suffering muscle injuries. Crestor is consider the most potent statin drug and was linked to the most reports of muscle injuries, according to the Food and Drug Administration’s adverse events database. Researchers analyzed data from that resource for reports between 2005 and 2011.

Generic drugs had the highest rate of adverse events in relation to the amount filed against name brand drugs. That could be due to the amount of prescriptions written for those drugs compared to those written for the more expensive name brands.

The study believes physicians should be searching for the lowest effective dose and potency of a statin drug that gets results for a patient to avoid the risk of muscle injuries.